Handbook of Pharmacogenomics and Stratified Medicine (ORIGINAL PDF from Publisher)

Handbook of Pharmacogenomics and Stratified Medicine (ORIGINAL PDF from Publisher)

The Handbook of Pharmacogenomics and Stratified Medicine, published by Elsevier Science, serves as a comprehensive guide to grasp the rapidly evolving field aimed at delivering precise drug dosages to individual patients at the appropriate time.

The handbook offers an intricate yet accessible overview of the entire domain, spanning from fundamental principles to practical applications in diverse medical conditions. Authored by international experts, the chapters cater to readers from various backgrounds – including clinical and non-clinical fields such as genetics, pharmacology, and ethics – enabling them to comprehend the underlying principles, achievements, setbacks, and forthcoming challenges in this realm.

To ensure broad accessibility, the clinical application segment initiates with a discussion on the disease process and current treatments, subsequently delving into the specifics of pharmacogenomics and stratified medicine.

Medicine constitutes the fundamental pillar of contemporary therapeutics, administered based on the premise that its advantages should outweigh potential risks.

Variability in individual responses to medications is a well-established fact, often leading to ambiguity in assessing the risk-benefit profile of specific drugs. The past decade has witnessed a genomic revolution characterized by technological advancements and the identification of genetic markers linked to various diseases. Concurrently, endeavors to enhance the safety and personalization of medical treatments have made significant strides, albeit with variations across medical disciplines.

Moreover, there is a growing interest within the pharmaceutical sector to harness pharmacogenomics for more efficacious and streamlined clinical drug development processes.

This resource furnishes both clinical and non-clinical researchers with practical insights that typically transcend their customary research domains or areas of expertise.

It encompasses a section on fundamental principles elucidating key concepts in genetics, genetic epidemiology, bioinformatics, pharmacokinetics, and pharmacodynamics.

Furthermore, the handbook covers cutting-edge technologies such as next-generation sequencing, proteomics, and metabolomics, alongside providing information on animal models, lymphoblastoid cell lines, and stem cells.

Detailed chapters addressing a wide array of medical conditions, implementation strategies, and regulatory considerations are included, along with discussions on the global implications of pharmacogenomics.

Handbook of Pharmacogenomics and Stratified Medicine (ORIGINAL PDF from Publisher)

Key Features

The book “Handbook of Pharmacogenomics and Stratified Medicine” encompasses several key features:

Comprehensive Coverage: This book delves deeply into pharmacogenomics, covering genetic fundamentals and their application in various disease contexts. Multidisciplinary Approach: Authored by international specialists, the book caters to a broad audience including clinicians, geneticists, pharmacologists, researchers, and industry experts, making it appealing to individuals with diverse backgrounds and knowledge.

Basic Principles: The “Handbook of Pharmacogenomics and Stratified Medicine” includes a segment dedicated to elucidating core genetic principles, genetic epidemiology, bioinformatics, and drug pharmacokinetics and pharmacodynamics. Emerging Technologies: Encompassing the latest genomic advancements like next-generation sequencing, proteomics, and metabolomics, the book offers readers insights into state-of-the-art research tools.

Disease-Specific Information: Detailed chapters within the “Handbook of Pharmacogenomics and Stratified Medicine” cover a wide array of disease conditions, providing perspectives on leveraging pharmacogenomics to improve treatment approaches and outcomes.

Regulatory Insights: This handbook explores the regulatory dimensions of pharmacogenomics, serving as a valuable resource for comprehending the guidelines and protocols governing this field. Global Implications: Discussions within the “Handbook of Pharmacogenomics and Stratified Medicine” examine the worldwide impact of pharmacogenomics, emphasizing its role in advancing drug development and clinical practices on a global scale.

Handbook of Pharmacogenomics and Stratified Medicine (ORIGINAL PDF from Publisher)

Summary