Clinical and Statistical Considerations in Personalized Medicine
Clinical And Statistical Considerations In Personalized Medicine delves into recent advancements in the realm of biomarkers and their translation into the clinical development sphere.
A group of leading clinicians, biostatisticians, regulators, commercial professionals, and researchers collectively examine the opportunities and hurdles associated with effectively implementing biomarkers in the realms of drug discovery, as well as preclinical and clinical development. The initial four chapters of the book concentrate on the development of biomarkers from a clinical standpoint.
These chapters cover topics ranging from the basics of biomarkers to breakthroughs in RNAi screens, epigenetics, and utilizing rare diseases as focal points for personalized medicine strategies. Subsequent sections of the book investigate the statistical nuances involved in the application of personalized medicine, encompassing aspects such as multiplicity in pharmacogenomics.
The final chapter of the book takes a deep dive into the regulatory complexities surrounding the utilization of biomarkers.
In the midst of a plethora of literature on biomarkers, there is a noticeable absence of a comprehensive publication that seamlessly integrates both the clinical and statistical dimensions.
This book stands out as one of the pioneering works that successfully merges the clinical and statistical facets of biomarkers within the personalized medicine framework.
Encompassing a broad spectrum of topics related to personalized medicine, it puts forth cutting-edge methodologies aimed at propelling the utilization of biomarkers in the realms of drug discovery and development. This publication not only aims to enhance patient care but also seeks to drive down costs and minimize the occurrence of adverse side effects.
It serves as a valuable resource for professionals and researchers seeking to deepen their understanding of biomarkers and their pivotal role in advancing healthcare practices.
Clinical and Statistical Considerations in Personalized Medicine
Key Features
The book “Clinical and Statistical Considerations in Personalized Medicine” encompasses a wide range of key features that contribute to its significance in the field.
With its comprehensive coverage, the book delves into various aspects of personalized medicine, both clinical and statistical, offering a valuable resource for professionals in healthcare and drug development.
The inclusion of expert contributors from diverse fields such as clinicians, biostatisticians, regulators, and commercial professionals enhances the book’s credibility by providing authoritative perspectives on personalized medicine and biomarkers.
Moreover, the book explores the development of biomarkers from a clinical perspective, discussing topics like RNAi screens, epigenetics, and the role of biomarkers in rare diseases, thereby enriching the reader’s understanding of this crucial area.
Additionally, it addresses the statistical considerations necessary for the successful implementation of personalized medicine, tackling challenges like multiplicity in pharmacogenomics to ensure accuracy and efficacy.
Furthermore, the book sheds light on the regulatory landscape surrounding biomarkers, offering insights into the complexities and requirements that govern their use in personalized medicine.
By integrating both clinical and statistical viewpoints, the book sets itself apart by providing readers with a holistic understanding of the subject, paving the way for a more comprehensive knowledge base.
Another significant aspect of the book is its aim to propel the application of biomarkers in drug discovery and development, with the ultimate goal of enhancing patient care, reducing healthcare costs, and minimizing adverse effects.
In essence, “Clinical and Statistical Considerations in Personalized Medicine” stands out as a pivotal resource that not only educates but also drives progress in the realm of personalized medicine, making it an indispensable asset for professionals and researchers alike.
Clinical and Statistical Considerations in Personalized Medicine
Summary
“Clinical and Statistical Considerations in Personalized Medicine” extensively explores the significance of biomarkers and their crucial role in the transition towards personalized medicine.
Edited by Claudio Carini, Sandeep M. Menon, and Mark Chang, this comprehensive book thoroughly investigates the clinical and statistical dimensions of biomarker development, starting from their initial identification to their effective integration into clinical settings.
The book delves into key subjects such as the obstacles encountered in biomarker research, breakthroughs in RNAi screens, the impact of epigenetics, and the utilization of biomarkers in the context of rare diseases.
Additionally, it sheds light on the pivotal statistical aspects, including the issue of multiplicity in pharmacogenomics, while also examining the regulatory challenges associated with the use of biomarkers.
“Clinical and Statistical Considerations in Personalized Medicine” provides valuable perspectives on how biomarkers can enhance patient care, lower healthcare expenses, and diminish adverse effects, positioning it as essential reading material for healthcare practitioners, researchers, and professionals engaged in the ever-evolving landscape of personalized medicine.
Clinical and Statistical Considerations in Personalized Medicine
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